If concomitant use of metoclopramide with atovaquone is considerably reduced atovaquone plasma concentration buy proviron. Concomitant use of metoclopramide with atovaquone not recommended. If the concomitant use of metoclopramide with bromocriptine bromocriptine increases the concentration in plasma. Metoclopramide tetracycline enhances absorption from the small intestine. Metoclopramide mexiletine enhances absorption and lithium. Metoclopramide reduces the absorption of cimetidine.
Caution should be exercised when using the drug Reglan in elderly patients.
From the nervous system may be extrapyramidal disorders, especially in children and young patients and / or at high doses, developing, usually at the beginning of treatment or after a single application. Use of the drug Reglan ® neoohodimo immediately cease in the event of occurrence of extrapyramidal symptoms. The reactions are fully reversible after cessation of treatment, however, may require symptomatic therapy (benzodiazepines in children and / or anticholinergic antiparkinsonian drugs in adults).
To avoid overdosing buy proviron observe the minimum interval between doses 6 h, even in the case of vomiting.
Prolonged treatment can lead to tardive dyskinesia, potentially irreversible, particularly in elderly patients. The treatment duration should not exceed 3 months due to the risk of tardive dyskinesia. Where there is evidence of tardive dyskinesia treatment should be stopped.
At the same time the use of metoclopramide with neuroleptics and metoclopramide monotherapy observed neuroleptic malignant syndrome. It is necessary to immediately discontinue for symptoms of neuroleptic malignant syndrome, and apply the appropriate therapy.
Caution should be exercised when used in patients with underlying neurological disorders and in patients taking drugs that affect the central nervous system.
When using buy proviron can also be celebrated symptoms of Parkinson’s disease.
reported cases of methemoglobinemia, which could be caused by a deficiency of the enzyme cytochrome-b5 reductase. In this case, must be promptly and fully to stop and take appropriate measures. Reported cases of severe serdechno¬sosudistyh side effects, including cardiovascular failure, bradycardia, heart failure and elongation buy proviron interval.
Caution should be exercised when applying in elderly patients, patients with cardiac disorders (including buy proviron prolongation), patients with impaired water and electrolyte balance, bradycardia, and in patients taking other drugs prolonging interval.
dose reduction is recommended in renal failure secondary to severe and severe hepatic insufficiency severity (see. “dosage and Administration” section).
Effects on ability to drive and use machines
Use caution when driving and other mechanisms. because the drug can cause drowsiness and dyskinesia.