buy proviron online

Time to maximum concentration after intramuscular administration -.. The value of 0,3-0,58 hour maximum concentration when administered intramuscularly at a dose of 400-500 mg is from 2.5 to 4 mg / ml
Quickly distributed in organs and tissues. The average retention time of the drug in the body by intramuscular injection -. 0.7-1.3 hours
is metabolized in the liver by glyukuronirovaniya. Detected 5 metabolites 3-hydroxypyridine phosphate (produced by the liver and involvement of alkaline phosphatase decomposed into phosphoric acid and 3-hydroxypyridin); 2nd metabolite is pharmacologically active and is detected in the urine for 1 to 2 hours after administration; 3rd – displayed in large amounts in the urine; 4th and 5th are glucuronic acid conjugates. Rapidly excreted in the urine primarily as metabolites (50% for 12 hours) and buy proviron online in small amounts – unchanged (0.3% in 12 hours). The most extensively excreted within the first 4 hours after ingestion. Performance in the urine excretion of unchanged drug and metabolites have considerable individual variability.

Indications
The drug is used in the complex therapy of:

 

  • anxiety in neurotic and neurosis-like states;
  • vascular dystonia;
  • encephalopathy;
  • acute stroke (ischemic stroke);
  • mild cognitive impairment atherosclerotic;
  • alcohol withdrawal syndrome with prevalence of neurosis and vegeto-vascular disorders;
  • acute intoxication by antipsychotic drugs;
  • acute myocardial infarction with the first day.Contraindications
  • Increased individual sensitivity to the drug;
  • severe hepatic and / or renal failure;
  • age of 18 years (effectiveness and safety have been established);
  • pregnancy;
  • during buy proviron online breastfeeding.Precautions
    Allergic diseases in history.

    Dosing and Administration
    The drug is administered intravenously or intramuscularly (for 5-7 minutes) or a drip (at a rate of 60 drops per minute).
    When the infusion method of administering a drug previously diluted in 200 ml 0.9% sodium chloride solution. The initial dose is 50-100 mg, 1-3 times per day with gradual increase to produce a therapeutic effect. The maximum daily dose – 800 mg. In acute violation of cerebral circulation injected intravenously 200-300 mg 1 time per day during the first 2-4 days, followed by intramuscular injection of 100 mg 3 times a day. In vascular encephalopathy (decompensation phase) injected bolus or infusion of 100 mg 2-3 times a day for 14 days, followed by intramuscular injection of 100 mg for 14 days. For foreign exchange prevention vascular encephalopathy administered by intramuscular injection of 100 mg 2 times a day for 10-14 days. Vegetative-vascular dystonia. neurotic and neurosis-like states: . drug is administered intramuscularly at 50-400 mg per day, course of treatment – 14 days When alcohol withdrawal syndrome is administered intramuscularly buy proviron online at 100-200 mg 2-3 times per day or by intravenous infusion of 100-200 mg 1-2 . times a day for 5-7 days the acute intoxication antipsychotic drugs administered intravenously at 50-300 mg per day for 7-14 days. Mild cognitive impairment: intramuscular injection of 100-300 mg per day for 14-30 days. acute myocardial infarction: the first 5 days of a drug administered by intravenous infusion over 30-90 minutes (100-150 ml 0.9% sodium chloride or 5% dextrose) or intravenously for at least 5 minutes. In the following 9 days the drug is administered intramuscularly 3 times a day (every 8 hours). The daily dose – 6.9 mg / kg / day, a single dose – 2.3 mg / kg.The maximum daily dose should not exceed 800 mg, single dose – 250 mg.